After upgrading to macOS 10.15 Catalina I had a little trouble with anaconda. In the end I traced it down to a change in the installation path of anaconda.
It now installed by default to /Users/USERNAME/opt/anaconda as opposed to /Users/USERNAME/anaconda
Small change, it did cause me about 30 minutes of head scratching until I looked at the installation path.
Might be useful to somebody.